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凋亡信號通路

細胞凋亡是指機體在生理或病理條件下,為了維持自身內環境的穩態,通過基因調控使細胞產生主動、有序的死亡;同時伴隨著一系列形態和生化方面的變化,包括核固縮、DNA片段化、細胞膜重塑和起泡、細胞皺縮、形成凋亡小體等,最后凋亡的細胞被巨噬細胞吞噬而消亡。在細胞凋亡整個過程中,質膜保持完整,細胞無內容物外溢,不引起炎癥反應。凋亡發生的途徑分為內源性線粒體途徑、內源性內質網途徑、外源性死亡受體途徑;或者某些條件下的granzyme B介導的凋亡過程。因此,了解細胞凋亡的機制有助于我們理解由細胞凋亡紊亂而造成疾病的發病機理。同時,也可能有助于開發與凋亡有關的基因或通路的靶向藥物。


名稱 貨號 Uniprot No. 種屬反應性 應用
AATF Antibody CSB-PA05264A0Rb Q9NY61 Human ELISA/IHC
ABL1 Antibody CSB-PA04355A0Rb P00519 Human ELISA/IHC/IP
ACAA2 Antibody CSB-PA001118LA01HU P42765 Human, Mouse, Rat ELISA/WB/IHC/IF/IP
ACSL5 Antibody CSB-PA891734HA01HU Q9ULC5 Human, Rat ELISA/WB/IHC
ACTL6A Antibody CSB-PA001236ESR2HU O96019 Human, Mouse ELISA/WB/IHC/CHIP
ACVR1C Antibody CSB-PA854112ESR1HU Q8NER5 Human, Mouse ELISA/WB/IHC
ADAMTSL4 Antibody CSB-PA761506ESR1HU Q6UY14 Human ELISA/IHC
ADRM1 Antibody CSB-PA001396HA01HU Q16186 Human, Mouse ELISA/WB/IHC/IF
AEN Antibody CSB-PA819883LA01HU Q8WTP8 Human ELISA/IF
AGER Antibody CSB-PA14209A0Rb Q15109 Human, Mouse ELISA/IHC/IF
AIFM1 Antibody CSB-PA001492HA01HU O95831 Human ELISA/WB/IHC/IF
AIM2 Antibody CSB-PA001499LA01HU O14862 Human ELISA/WB/IHC/IF
AIMP1 Antibody CSB-PA618638DSR1HU Q12904 Human ELISA/WB/IHC/IP
AIMP2 Antibody CSB-PA819153ESR1HU Q13155 Human ELISA/WB/IHC
AK6 Antibody CSB-PA619078ESR1HU Q9Y3D8 Human ELISA/WB/IHC
AKT1 Antibody CSB-PA15905A0RB P31749 Human ELISA/IHC/IF/ChIp
AKT2 Antibody CSB-PA15919A0Rb P31751 Human, Rat ELISA/WB/IHC/IF
AKT3 Antibody CSB-PA15929A0Rb Q9Y243 Human, Mouse ELISA/IP
AKTIP Antibody CSB-PA862043ESR2HU Q9H8T0 Human ELISA/IHC
ALKBH8 Antibody CSB-PA842644ESR1HU Q96BT7 Human ELISA/IHC

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IF
CAMLG Antibody
CSB-PA004475LA01HU
S1PR3 Antibody
CSB-PA859932LA01HU
NUPR1 Antibody
CSB-PA527662LA01HU
FATE1 Antibody
CSB-PA839274LA01HU

IHC
KRT18 Antibody
CSB-PA10629A0Rb
WISP1 Antibody
CSB-PA026119LA01HU
DRAM1 Antibody
CSB-PA836675LA01HU
XPO1 Antibody
CSB-PA026221LA01HU

WB
TMBIM1 Antibody
CSB-PA853376LA01HU
ACTL6A Antibody
CSB-PA001236ESR2HU

IP
CDK2 Antibody
CSB-PA005061LA01HU
EIF3F Antibody
CSB-PA007535ESR2HU
TIA1 Antibody
CSB-PA023527DSR1HU
AIMP1 Antibody
CSB-PA618638DSR1HU

ChIP
NFKB1 Antibody
CSB-PA10354A0Rb
AKT1 Antibody
CSB-PA15905A0RB